Tandospirone enteric

TL;DR: The tandospirone enteric-coated mini-pills are particularly suitable for the patients suffering from anxiety caused by digestive system diseases, the patients who suffer from gastric mucosal lesion and are easy to bleed, and senile patients who need to take medicines for a long time to take as mentioned in this paper.

Abstract: The invention provides tandospirone enteric-coated mini-pills and a preparation method thereof. The enteric-coated mini-pills are prepared by adding pharmaceutically acceptable auxiliary materials into an active ingredient, namely the tandospirone or medicinal salt thereof. The invention also provides application of the tandospirone enteric-coated mini-pills to preparation of medicines which are administrated intestinally and can resist anxiety. The tandospirone enteric-coated mini-pills prepared by the method have stable quality, are not disintegrated in a stomach, and have a large distribution area in an intestinal tract, high disintegration and dissolution property, high bioavailability, low irritability on a gastrointestinal mucous membrane, few side effects and high medicine taking compliance of a patient. The tandospirone enteric-coated mini-pills can be used for treating patients suffering from the following diseases: an anxiety state caused by various neuroses, an anxiety state accompanied with body diseases, such as primary hypertension and peptic ulcer, and mild and moderate depression; and the tandospirone enteric-coated mini-pills are particularly suitable for the patients suffering from anxiety caused by digestive system diseases, the patients who suffer from gastric mucosal lesion and are easy to bleed, and senile patients who need to take medicines for a long time to take.